Intermediate Organic Chemistry - Part 2

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Intermediate Organic Chemistry - Part 2

Coursera (CC)
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Description

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Organic chemistry course covering intermediate topics in structure and reactivity with special applications to the life sciences.

About the Course

This course covers topics on the structure and reactivity of organic compounds with an emphasis on bioorganic chemistry and applications to life sciences. Stereochemical concepts and aspects of non-covalent interactions relevant to enzyme-catalyzed reactions are presented. The mechanistic approach of this course is designed to help students build intuition about how bioorganic compounds undergo their chemical transformations. The structure and reactivity of the major classes of bioorganic molecules - proteins, carbohydrates, and nucleic acids - w…

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When you enroll for courses through Coursera you get to choose for a paid plan or for a free plan

  • Free plan: No certicification and/or audit only. You will have access to all course materials except graded items.
  • Paid plan: Commit to earning a Certificate—it's a trusted, shareable way to showcase your new skills.

Organic chemistry course covering intermediate topics in structure and reactivity with special applications to the life sciences.

About the Course

This course covers topics on the structure and reactivity of organic compounds with an emphasis on bioorganic chemistry and applications to life sciences. Stereochemical concepts and aspects of non-covalent interactions relevant to enzyme-catalyzed reactions are presented. The mechanistic approach of this course is designed to help students build intuition about how bioorganic compounds undergo their chemical transformations. The structure and reactivity of the major classes of bioorganic molecules - proteins, carbohydrates, and nucleic acids - will be covered in detail. An introduction to biosynthesis will be presented, along with the use of contemporary literature and structural databases. Throughout the course, emphasis will be placed on mechanism-based problem-solving skills to help students understand and think critically about the organic chemistry of living systems. This course, orgchem2b, and its prerequisite, orgchem2a, are equivalent to a second-semester organic chemistry course; these courses are well suited for students in agricultural, nutritional and biological sciences, as well as premedical, predental, and preveterinary programs.

About the Instructor(s)

Professor Moore received his B.S. degree in Chemistry in 1984 and his Ph.D. in Materials Science in 1989 from the University of Illinois. Thereafter, he was an NSF Postdoctoral Fellow at Caltech and an assistant professor at the University of Michigan before joining the faculty in 1993. Professor Moore is the author of over 300 publications, a Fellow of the American Chemical Society, a Member of the American Academy of Arts and Sciences and an Associate Editor of the Journal of the American Chemical Society.

Course Syllabus

Lesson

Topic

1

Topic Relationships

2

Prochirality

3

Amino Acids

4

3D Protein Structure & Noncovalent Interactions

5

Peptide Chemistry

6

Enzyme Catalysis

7

Enzyme Mechanisms

8

Enzyme Inhibition

9

Enzyme Stereochem.

10

Enzymatic Elimin.

11

Biosynthesis

12

Exam Review

13

Monosaccharides

14

Carbohydrate Reactions

15

Oligosaccharides

16

Nucleic Acids

17

Bioorganic Phosphorus

18

Protein Biosynthesis

19

Literature & Databases

20

Exam Review

Recommended Background

One semester of organic chemistry and orgchem2a.

Course Format

Content is delivered via 5-minute videos we call webcasts. Webcasts of a related theme, along with a set of PDF lecture notes, constitute a lesson. There are 20 lessons in the course. Students are expected to watch and study these materials independently, much as they would study a traditional textbook. We encourage students to comment with feedback or questions via the discussion board. 
Bundled with each lesson are problems designed to help students test their understanding of webcast material and apply their knowledge to new situations. All problems in the course are delivered to students electronically and machine graded with real-time feedback. Problems of the Day are covered by instructors during class time and emphasize the acquisition of skills, strategies, and attitudes for heuristic (non-algorithmic) problem solving. Pressure Point Problems, or "P3s," are more difficult, timed problems that help students prepare for exam situations. Because training effective problem solvers is one of our primary goals, we strongly emphasize tackling and understanding the problems associated with each lesson. 
Placing lecture contents online has allowed us to use class time almost exclusively to sharpen students' problem solving abilities. During 
discussion sessions, students and instructors communicate online through web-based conferencing technology. Using this technology, we are able to run discussion sessions for large numbers of students while maintaining an interactive, engaging learning environment. In all discussion sessions, the emphasis is on student activity and participation.

FAQ

  • Will I get a certificate for this course?

    Yes. Students who successfully complete the class will receive a certificate signed by the instructor.

Provided by:

University: University of Illinois at Urbana-Champaign

Instructor(s): Jeffrey S. Moore

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